Additional Basal Rates Used in Insulin Pump Therapy Does Not Improve A1C in Adult Patients with Type 1 Diabetes

作者：Tildesley Hugh D; Chan Jeremy H M; Mazanderani Adel B; Wright Anthony M; Tildesley Hamish G; Pottinger Betty

来源：Canadian Journal of Diabetes, 2012, 36(1): 25-26.

DOI：10.1016/j.jcjd.2012.01.004

• basal rates
• type 1 diabetes
• insulin pump therapy

Objective: To determine whether, in adult patients with type 1 diabetes using an insulin pump, there is a statistically significant difference of the mean glycated hemoglobin (A1C) levels between patients utilizing a different number of basal rates.
Methods: We performed a retrospective chart review from 2008 to 2011 of patients on insulin pump therapy. One hundred sixty-eight patients who had had type 1 diabetes mellitus for at least 2 years and had been on pump therapy for at least 3 months were studied.
Results: We found no statistically significant difference of mean A1C values between patients utilizing a different number of basal rates (p=0.21).
Conclusion: There does not appear to be a relationship between the number of basal rates prescribed and outcome as measured by A1C in adult patients with type 1 diabetes on insulin pump therapy. In a large proportion of patients (38%), a single basal rate was as effective as multiple basal rates as measured by A1C values.

• 出版日期2012-2