Phosphine triggered [3+2] allenoate-acrylate annulation: a mechanistic enlightenment

作者：Mercier Evan; Fonovic Branden; Henry Chris; Kwon Ohyun^*; Dudding Travis

来源：Tetrahedron Letters, 2007, 48(20): 3617-3620.

DOI：10.1016/j.tetlet.2007.03.030

A mechanistic study of phosphine-mediated [3+2] annulation of allenoate and acrylate is presented. The insight gained has identified that (1) [3+2] cycloaddition proceeds through a stepwise mechanism and (2) the involvement of a molecule of water, which services as a proton-shuttle, is essential for annulated product formation.

• 出版日期2007-5-14