A New Diagnostic Sensor for Acetone in Urine

作者：Felice Carl; Lein Gina; Santhanam Kalathur S V^*; Fuller Lynn

来源：Materials Express, 2011, 1(3): 219-224.

DOI：10.1166/mex.2011.1031

• Diabetes Mellitus
• Ketosis
• Detection Acetone in Urine
• Resistive Sensor
• Carbon Nanotube Composite

A new resistive conducting polymer sensor has been developed for the diagnosis of diabetes mellitus-ketosis that requires an analysis of the urine sample. It involves the measurement of resistance of the sensor in a chamber containing the urine sample. The sensor is constructed with an active composite material made of 10 mg of multiwalled carbon nanotube mixed with 0.5% nafion solution in ethanol through a process of sonication and subsequent deposition between two gold electrodes. The resistance of the sensor increases in the presence of acetone that is linear in the concentration range of 5 micromolar to 25 millimolar concentration in two steps. For the practical diagnosis the sensor operates well in the concentration range of 30 mg/dL to 80 mg/dL that is specific to diabetes mellitus and ketosis. The presence of ethanol in urine will not interfere with the measurement. The response time of the sensor is about 200 seconds. The sensor can be reused after flushing with nitrogen gas. The mechanism of sensor operation has been examined by Fourier Infrared Spectroscopy which suggests that acetone adsorption and desorption is producing the sensor action.

• 出版日期2011-9