MAPPING OF THE HUMAN GSPT1 GENE, A HUMAN HOMOLOG OF THE YEAST GST1 GENE, TO CHROMOSOMAL BAND 16P13.1

作者：OZAWA K^*; MURAKAMI Y; EKI T; YOKOYAMA K; SOEDA E; HOSHINO S; UI M; HANAOKA F

来源：Somatic Cell and Molecular Genetics, 1992, 18(2): 189-194.

DOI：10.1007/BF01233164

The GSPT1 gene, a human homolog of the yeast GST1 gene (formerly named GST1-Hs), was mapped on human chromosome 16p13.1 by a combination of nonradioactive in situ hybridization and Giemsa staining. Southern blot hybridization with a panel of human-rodent somatic cells confirmed the location of the GSPT1 gene on chromosome 16 and also showed the existence of a homologous gene on the X chromosome. A breakpoint for nonrandom chromosome rearrangements has been found in the region of GSPT1 in patients with acute nonlymphocytic leukemia.

• 出版日期1992-3