New evidence on intake of multivitamin and multimineral supplements in a population over 50

作者：Bernabei R^*; Martone A M

来源：Giornale di Gerontologia, 2014, 62(6): 500-505.

• Multivitamin supplements
• Prevention
• Chronic disease

The demographic changes occurred in recent decades have resulted in a significant increase in the number of older-adults suffering from a range of chronic-degenerative diseases. %26lt;br%26gt;These represent a major cause of access to medical services as well as an important part of national health expenditure. A proper and balanced diet, together with regular physical activity, appears to play a protective role against most of these diseases. Several studies have shown that vitamin deficiency is associated with a higher incidence and prevalence of obesity, cardiovascular disease, diabetes mellitus type II, dementia, osteoporosis, cataract and macular degeneration. The restoration of adequate levels of these micronutrients seems to have a beneficial effect in terms of prevention of these diseases. %26lt;br%26gt;The PHS II trial is the first independent study collecting evidence on daily and long term intake of multivitamin and multimineral supplements in terms of safety and efficacy, analyzing their effect on the incidence of cardiovascular events and malignancy. %26lt;br%26gt;Findings from PHS II indicate that multivitamin supplementation is safe and may reduce the incidence of malignancy.

• 出版日期2014-12