Acute kidney injury requiring dialysis secondary to adenovirus nephritis in renal transplant recipient

作者：Sujeet K; Vasudev B; Desai P; Bellizzi J; Novoa Takara L; He C; El Meanawy A^*

来源：Transplant Infectious Disease, 2011, 13(2): 174-177.

DOI：10.1111/j.1399-3062.2010.00577.x

• adenovirus
• disseminated
• nephritis
• transplant
• cidofovir

P>Disseminated adenoviral infection is a serious problem, especially in an immunocompromised host. The disease carries a mortality rate reaching as high as 80%. It is seen most frequently in bone marrow transplant recipients, where it causes pneumonia and disseminated disease. In solid organ transplant recipients it causes graft infection. We report the case of a renal transplant recipient with disseminated adenoviral infection and acute kidney failure requiring dialysis. Reduction of immunosuppression and 1 dose of cidofovir were associated with resolution of viremia and viruria and return of kidney function to near baseline.

• 出版日期2011-4