An Evidence-Based Review of Related Metabolites and Metabolic Network Research on Cerebral Ischemia

作者:Liu Mengting; Tang Liying; Liu Xin; Fang Jing; Zhan Hao; Wu Hongwei*; Yang Hongjun*
来源:Oxidative Medicine and Cellular Longevity, 2016, 2016: 9162074.
DOI:10.1155/2016/9162074

摘要

In recent years, metabolomics analyses have been widely applied to cerebral ischemia research. This paper introduces the latest proceedings of metabolomics research on cerebral ischemia. The main techniques, models, animals, and biomarkers of cerebral ischemia will be discussed. With analysis help from the MBRole website and the KEGG database, the altered metabolites in rat cerebral ischemia were used for metabolic pathway enrichment analyses. Our results identify the main metabolic pathways that are related to cerebral ischemia and further construct ametabolic network. These results will provide useful information for elucidating the pathogenesis of cerebral ischemia, as well as the discovery of cerebral ischemia biomarkers.

  • 出版日期2016
  • 单位中国中医科学院