Second meiotic arrest and exit in frogs and mice

作者：Perry Anthony C F^*; Verlhac Marie Helene

来源：EMBO Reports, 2008, 9(3): 246-251.

DOI：10.1038/embor.2008.22

• metaphase II
• Emi2
• cytostatic factor
• vertebrate meiosis
• fertilization

Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus, and compare and contrast them with their counterparts in mice.

• 出版日期2008-3