Amberlyst-15: an efficient and reusable catalyst for the Friedel-Crafts reactions of activated arenes and heteroarenes with alpha-amido sulfones

作者：Kadam Santosh T; Thirupathi Ponnaboina; Kim Sung Soo^*

来源：Tetrahedron, 2009, 65(50): 10383-10389.

DOI：10.1016/j.tet.2009.10.044

• alpha-Amido sulfones
• Friedel-Crafts reaction
• Amberlyst-15
• Heterogeneous catalyst

The heterogeneous Amberlyst-15 catalyst displays efficient catalytic properties for the Friedel-Crafts reactions between an activated arenes or heteroarenes and of alpha-amido, sulfones. Various alpha-amido sulfones on treatment with 1,2,4-trimethoxy benzene give the Friedel-Crafts reaction products in very good yield. The reactions with heteroarenes show moderate yield of the product. The catalyst can be easily recycled without significant loss of activity.

• 出版日期2009-12-12