A new Hantaan-like virus in rodents (Apodemus peninsulae) from Northeastern China

作者：Jiang Jia Fu; Zhang Wen Yi; Yao Kun; Wu Xiao Ming; Zuo Shu Qing; Zhan Lin; Zhang Pan He; Cao Wu Chun^*

来源：Virus Research, 2007, 130(1-2): 292-295.

DOI：10.1016/j.virusres.2007.05.021

• Apodemus peninsulae
• hantavirus
• amur virus
• HFRS

Lung tissue samples of 76 Korean field mice (Apodemus peninsulae) collected from northeastern China bordering with Far East Russia and Korea were detected for hantavirus partial M-segment or entire S-segment sequences by RT-PCR and 481-nt mitochondrial DNA fragment of the rodents. Four A. peninsulae mice were found positive for partial M-segment of hantavirus. Sequence analyses of partial M-segment or/and entire S-segment of the hantaviruses revealed that three were closely related to Hantaan virus (HTNV) strain 76-118. One new variant of HTNV-Iike virus designated as "Jilin-AP06" was much different from other rodent-borne hantavirus from China, and clustered with Amur (AMR) virus strains. which represent a distinct genetic lineage. These findings imply that hantavirus Jililn-AP06 strain from A. peninsulae is a new record of rodent-borne AMR virus in China. A. peninsulae might be a natural carrier of two distinct hantaviruses, AMR virus and HTNV in China.

• 出版日期2007-12