Promoting helicity in carbohydrate-containing foldamers through long-range hydrogen bonds

作者:Rodriguez Lucena David; Benito Juan M; Ortiz Mellet Carmen; Garcia Fernandez Jose M
来源:Chemical Communications, 2007, (8): 831-833.
DOI:10.1039/b614294j

摘要

A sensor system to probe the propensity of carbohydrates to induce helical structures through long-range hydrogen bonds, based on a C-2-symmetric xylylene bis(thiourea) arrangement, is reported; the formation of intermolecular complexes with benzoate anion promotes helix uncoiling, the free energy of the process being related to helix stability.

  • 出版日期2007