A Water-Soluble Fluorescent Probe for SO2 Derivatives in Aqueous Solution and Serum Based on Phenanthroimidazole Dye

作者:Zhou, Yang; Wang, Ying; Xiao, Shuzhang; He, Xiafeng; Zhang, Nuonuo; Li, Dejiang; Zheng, Kaibo*
来源:Journal of Fluorescence, 2017, 27(3): 799-804.
DOI:10.1007/s10895-016-2015-9

摘要

A water-soluble fluorescent SO2 derivatives probe PI-SO (2) based on a phenanthroimidazole dye, and a sensitive SO2 recognition site, aldehyde was constructed. The probe PI-SO (2) exhibits desirable properties such as high sensitivity, high selectivity and good water-solubility. Significantly, we have demonstrated that the probe PI-SO (2) is suitable for rapidly fluorescence detecting of SO2 derivatives in aqueous solution and serum. The application of the novel probe PI-SO (2) proved that it was not only a useful tool for the detection of SO2 derivatives in vitro, but also a potential assay for investigating the effects of SO2 derivatives, and demonstrating its value in practical applicationin of complex biological samples.