Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports

作者:Huang Sheng; Zhao Weiliang; Wang Zihua; Tao Kai*; Liu Xiaoyan; Chang Peng*
来源:Molecular Medicine Reports, 2016, 13(2): 1063-1069.
DOI:10.3892/mmr.2015.4682

摘要

Cell-assisted lipotransfer (CAL) has been widely used in various clinical applications, including breast augmentation following mammectomy, soft-tissue reconstruction and wound healing. However, the clinical application of CAL has been restricted due to the transplanted fat tissues being readily liquefied and absorbed. The present review examines 57 previously published studies involving CAL, including fat grafting or fat transfer with human adipose-stem cells in all known databases. Of these 57 articles, seven reported the clinical application of CAL. In the 57 studies, the majority of the fat tissues were obtained from the abdomen via liposuction of the seven clinical studies, four were performed in patients requiring breast augmentation, one in a patient requiring facial augmentation, one in a patient requiring soft tissue augmentation/reconstruction and one in a patient requiring fat in their upper arms. Despite the potential risks, there has been an increased demand for CAL in in cosmetic or aesthetic applications. Thus, criteria and guidelines are necessary for the clinical application of CAL technology.

  • 出版日期2016-2
  • 单位中国人民解放军第二军医大学; 中国人民解放军南京军区福州总医院; 天津市中医药研究院附属医院; 中国人民解放军沈阳军区总医院

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