Detection of regional blood flow in borderline personality disorder

作者：Koese Ruguel; Abay Ercan; Altun Guelay Durmus

来源：Anadolu Psikiyatri Dergisi, 2010, 11(2): 102-111.

• borderline personality disorder
• single photon emission computed tomography
• affective disturbance
• impulsive aggression

Objective: To assess the role of SPECT (Single Photon Emission Computed Tomography) in the diagnosis of BPD (borderline personality disorder). Methods: Twenty BPD patients assessed with SCID-CV (Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition Axis I Disorders, Clinical Version) and had no comorbid diagnoses have been assessed with SPECT, these images were compared to the cerebral blood flow of 17 healthy individuals. The patients' SPECT images were also assessed according to the clinical data that has been gathered via SCID-II (Personality Disorders assessment of Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-Third Edition-Revised) of patients. Results: BPD patients cerebral blood flow differed from the controls' and showed corticolimbic dysfunction. Conclusion: As the dysfunction is compatible with the disorder's core symptoms, neuroimaging studies can contribute to the endophenotype studies which take into consider the clinical dimensions of BPD. (Anatolian Journal of Psychiatry 2010; 11:102-111)

• 出版日期2010