An invariant allocation function for multi-treatment clinical trials

作者：Bandyopadhyay Uttam; Bhattacharya Rahul^*

来源：Statistics and Its Interface, 2016, 9(1): 1-10.

DOI：10.4310/sii.2016.v9.n1.a1

• Response adaptive allocation
• Clinical trial
• Censoring

An allocation function, invariant under monotonic transformation, is proposed in the context of multi-arm clinical trials for a class of continuous response distributions. The aim is to skew the allocation towards the most promising treatment using the whole information about the response distributions. A response adaptive implementation based on the proposed allocation function is suggested and assessed through some useful performance measures.

• 出版日期2016