Au nanorods modulated NIR fluorescence and singlet oxygen generation of water soluble dendritic zinc phthalocyanine

作者：Zhou, Xuefei; He, Xiaohong; Wei, Shiliang; Jia, Kun^*; Liu, Xiaobo^*

来源：Journal of Colloid and Interface Science, 2016, 482: 252-259.

DOI：10.1016/j.jcis.2016.07.072

• Zinc phthalocyanine
• Gold nanorods
• Self-assembling
• Plasmonics
• NIR fluorophores

A novel cyano-terminated zinc phthalocyanine (ZnPc-CN) exhibiting visible near infrared (vis-NIR) emitting around 690 nm in N,N-dimethylformamide (DMF) solvent has been synthesized. Furthermore, the peripheral cyano groups of newly synthesized zinc phthalocyanine were hydrolyzed in strong basic solution, leading to water soluble carboxylated zinc phthalocyanine (ZnPc-COOH) with completely quenched fluorescence in aqueous solution. Interestingly, we found that the NIR fluorescence of aqueous ZnPc-COOH was dramatically recovered in the presence of gold nanorods (Au NR), which was due to the alternation of ZnPc-COOH molecules self-assembling via electrostatic interaction between cetyltrimethylammonium bromide (CTAB) on the surface of Au NR and peripheral carboxyl of ZnPc-COOH. In addition, ZnPc-COOH/Au NR conjugates demonstrated an improved singlet oxygen generation, which could be served as potential bioimaging probe and photosensitizer for photodynamic therapy.

• 出版日期2016-11-15
• 单位电子科技大学