A cortical dysembryoplastic neuroepithelial tumor initially occurring in the periventricular white matter

作者：Kawataki Tomoyuki^*; Sato Eiji; Kato Tatsuya; Sato Takashi; Horikoshi Toru; Kinouchi Hiroyuki

来源：Journal of Neurosurgery-Pediatrics, 2010, 6(6): 600-603.

DOI：10.3171/2010.10.PEDS10391

• dysembryoplastic neuroepithelial tumor
• calcification
• subependymal layer

In this report a rare case of dysembryoplastic neuroepithelial tumor (DNET) initially presented as a small white matter lesion with calcification adjacent to the lateral ventricle and extending to the frontal cortex after 7 years This 1-year-old boy initially suffered from partial seizures Initial CT revealed a small low-density area surrounding a tiny calcified mass in the deep white matter of the left frontal lobe Seven years later, his seizures had become intractable to antiepileptic agents, and MR imaging demonstrated a relatively large mass extending from the calcified lesion up to the adjacent cortical surface He underwent surgery and the tumor was subtotally removed Histological examination of the tumor verified it as a DNET consisting of clusters of small oligodendrocytes with floating neurons in the mucoid background The pattern of the tumor progression in this case suggests that a DNET in the cortex originates from the subependymal germinal layer near the ventricle (DOI 10.3171/2010.10.PEDS10391)

• 出版日期2010-12