科研之友
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摘要
We have identified a new mechanism for the cleavage and activation of nonribosomally made peptides and peptidepolyketide hybrids that are apparently operational in several different bacteria. This process includes the cleavage of a precursor molecule by a membrane-bound and d-asparagine-specific peptidase, as shown here in the biosynthesis of the antibiotic xenocoumacin from Xenorhabdus nematophila.
- 出版日期2011-12
- 单位国家气候中心
