A genomewide survey of developmentally relevant genes in Ciona intestinalis - IV. Genes for HMG transcriptional regulators, bZip and GATA/Gli/Zic/Snail

作者：Yamada L; Kobayashi K; Degnan B; Satoh N; Satou Y^*

来源：Development Genes and Evolution, 2003, 213(5-6): 245-253.

DOI：10.1007/s00427-003-0316-x

• basal chordates
• bZip
• Ciona intestinalis
• GATA/Gli/Zic/Snail
• genomewide survey
• HMG transcriptional regulators

Many kinds of transcription factors and regulators play key roles in a variety of developmental processes. In the present survey, genes encoding proteins with conserved HMG-box, bZip domains, and some types of zinc finger motifs were surveyed in the completely sequenced genome of Ciona intestinalis. In the present analysis, 21 HMG-box-containing genes and 26 bZip genes were identified as well as four small groups of zinc finger genes in the Ciona genome. The results also showed that a less redundant set of genes is present in the Ciona genome compared with vertebrate genomes. In addition, cDNA clones for almost all genes identified have been cloned and distributed as a "Ciona intestinalis Gene Collection Release I". The present comprehensive analysis therefore provides a means to study the role of these transcription factors in developmental processes of basal chordates.

• 出版日期2003-6