An insulin-binding protein from the venom of a solitary wasp Eumenes pomiformis binds to apolipophorin III in lepidopteran hemolymph

作者：Baek Ji Hyeong; Lee Si Hyeock^*; Kim Woe Yeon; Kim Min Gab^*

来源：Toxicon, 2016, 111: 62-64.

DOI：10.1016/j.toxicon.2015.12.019

• Venom
• Solitary hunting wasp
• Insulin-binding protein
• EpIBP
• Apolipophorin III

EpIBP, an insulin-like peptide-binding protein, is a major protein component of the venom of a solitary hunting wasp, Eumenes pomiformis. To evaluate the bioactivity, bacteria-expressed EpIBP was injected into Spodoptera exigua larvae, resulting in a higher survival rate and reduced loss of body weight under starvation conditions than control larvae. EpIBP was found to interact with apolipophorin III (apoLp III), implying that EpIBP might function by altering the apoLp III-mediated metabolism of prey.

• 出版日期2016-3-1