Acquired echinocandin resistance in a Candida krusei blood isolate confirmed by mutations in the fks1 gene

作者：Prigitano Anna; Esposto Maria Carmela; Cogliati Massimo; Pitzurra Lucia; Santamaria Concetta; Tortorano Anna Maria^*

来源：New Microbiologica, 2014, 37(2): 237-240.

• Candida krusei
• Echinocandin resistance
• Gene mutation

We describe a case of bloodstream infection caused by a Candida krusei strain that developed echinocandin resistance during caspofungin therapy. Three mutations were found in the HS1 region of the fks1 gene, two of them have never been reported either in C. krusei nor in C. albicans.

• 出版日期2014-4