Autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease in a child Case report and review of the literature

作者：Sedej Katarina; Toplak Natasa^*; Praprotnik Marina; Luzar Bostjan; Brecelj Jernej; Avcin Tadej

来源：Pediatric Rheumatology, 2015, 13(1): 47.

DOI：10.1186/s12969-015-0046-4

• Mixed connective tissue disease
• Autoimmune hepatitis
• Child

Background: Liver disease is rare in the course of mixed connective tissue disease. Most commonly liver steatosis or elevated liver function tests are reported and only a few cases of mixed connective tissue disease associated with autoimmune hepatitis were described.
Case presentation: We report a case of an 11-year old boy with hepatitis on admission to the hospital and symptoms and signs of mixed connective tissue disease. Autoimmune hepatitis has been confirmed by liver biopsy.
Conclusion: To the best of our knowledge this is the youngest patient with autoimmune hepatitis as a presenting manifestation of mixed connective tissue disease.

• 出版日期2015-11-10