Blood HCO3- concentration predicts the long-term prognosis of acute kidney injury patients

作者：Che, Xiajing; Xie, Yuanyuan; Wang, Chunlin; Wang, Qin; Zhang, Minfang; Qi, Chaojun; Ni, Zhaohui; Mou, Shan^*

来源：Biomarkers in Medicine, 2014, 8(10): 1219-1226.

DOI：10.2217/BMM.14.91

• acute kidney injury (AKI)
• blood HCO3
• (-) concentration
• combined markers
• Cox regression analysis
• follow-up
• Kaplan-Meier method
• prevention
• receiver operating characteristic-area under the curve
• renal prognosis

Aim: To evaluate the value of HCO3 (-) concentrations in long-term prognosis after acute kidney injury. Patients & methods: A total of 169 AKI patients were included in this study. At the 12-month follow-up, the patients were divided into recovered and unrecovered groups. Results: The blood HCO3 (-) concentrations were significantly correlated with poor prognosis. The area under the curve for renal prognosis of 6 months later blood HCO3 (-) concentrations was 0.798. Combined HCO3 (-) and Scr level area under the curve was 0.952. Conclusion: The blood HCO3 (-) level was useful in evaluating renal prognosis of acute kidney injury patients. The combination of blood HCO3 (-) concentration and Scr level increased the accuracy of prediction.

• 出版日期2014
• 单位上海交通大学