Highly sensitive and selective electrochemical sensor based on high-quality graphene/nafion nanocomposite for voltammetric determination of nebivolol

作者：Er Engin; Celikkan Huseyin^*; Erk Nevin

来源：Sensors and Actuators B: Chemical , 2016, 224: 170-177.

DOI：10.1016/j.snb.2015.10.028

• Graphene
• Electrochemical nanosensor
• Stripping voltammetry
• Modified electrode
• Electroanalysis
• Nebivolol

This research is concerned with the development of a facile, highly selective and sensitive graphene-based electrochemical nanosensing material for the detection of nebivolol (NBV). It is the first report that the electrochemical behaviour and quantitative analysis of NBV were investigated in detail on high-quality graphene/nafion nanocomposite modified electrode (GRE/NFN) using voltammetric techniques. The structure of high-quality graphene (GR) was characterized by Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA) and transmission electron microscopy (TEM). A broad peak at 1025 mV and well-defined peak at 1325 mV were observed by adsorptive stripping differential pulse voltammetry (AdsDPV) on GRE/NFN in the detection of NBV. Considering that the peak appeared at 1325 mV, GRE/NFN showed that NBV had a high electrocatalytic performance towards the NBV in the linear range from 0.5 to 24.0 mu M with a low detection limit of 46 nM under the optimal experimental conditions. The GRE/NFN could be a promising material with high sensitivity and selectivity for the electrochemical sensing of NBV and can also be adopted to determine NBV in pharmaceutical and clinical samples.

• 出版日期2016-3-1