Atopic dermatitis and aeroallergens

作者：Engel F^*; de Blay F

来源：Revue Francaise d Allergologie, 2010, 50(8): 621-627.

DOI：10.1016/j.reval.2010.03.011

• Atopic dermatitis
• Aeroallergens
• Sensitization
• Avoidance
• Atopy Patch Test
• Skin barrier
• Filaggrin

Atopic dermatitis (AD) is often associated with sensitization to aeroallergens, but the role of sensitization in the development of eczema is still controversial. However, in a subgroup of patients with AD, eczematous skin lesions can be induced by epicutaneous testing with aeroallergens, a procedure named Atopy Patch Test (APT). Exposure to aeroallergens can exacerbate or maintain the disease, and APTs are probably useful to identify this triggering factor. APTs show a higher specificity than skin prick-tests. IgE-sensitization is not a necessary prerequisite for the development of AD. Avoidance of house-dust-mite does not show any preventive effect on the onset or progression of AD. The studies are generally negative in primary prevention and inconsistent in secondary prevention.

• 出版日期2010-12