Association of Eosinophilic Gastrointestinal Disorders with Other Atopic Disorders

作者：Jyonouchi Soma; Brown Whitehorn Terri A; Spergel Jonathan M^*

来源：Immunology and Allergy Clinics of North America, 2009, 29(1): 85-+.

DOI：10.1016/j.iac.2008.09.008

• Eosinophilic esophagitis
• Atopy
• Asthma
• Food allergy
• Atopic dermatitis

Eosinophilic esophagitis is a chronic disease that leads to either persistent symptoms or, at times, intermittent "flares." It shares many features with other atopic diseases (asthma, allergic rhinitis, and atopic dermatitis), including the following: T helper 2 cells and eosinophils play a critical role in the pathogenesis of the disease; avoidance of allergens promotes remission of disease and symptom control; and locally applied corticosteroids provide control. Finally, most patients who have eosinophilic gastrointestinal disorders have an associated atopic disease.

• 出版日期2009-2