A Comparison of Antibiotic Serum Concentrations Drawn Simultaneously from Peripherally Inserted Central Catheters and Peripheral Veins in Children with Respiratory Infection

作者：Green, Mary Ellen^*; Sullivan, Keri J; Wells, Sarah; Board, Rhonda; Feldman, Henry A; McCabe, Margaret

来源：Journal of Pediatric Nursing-Nursing Care of Children & Families, 2015, 30(6): 868-876.

DOI：10.1016/j.pedn.2015.07.011

• Antibiotic levels
• PICC
• Venipunctures
• Respiratory illness
• Cystic fibrosis
• CVC
• Vancomycin
• Tobramycin

The purpose of the study was to evaluate serum concentration of antibiotics drawn from a peripherally inserted central catheter (PICC) compared with a peripheral venipuncture. This prospective comparative study included patients with ages 1 month to 21 years admitted with a respiratory infection requiring IV vancomycin or IV tobramycin via a newly placed PICC. The difference between the antibiotic levels from the venipuncture and PICC samples was statistically significant for both the peak and trough levels. However, the difference in values was not enough to impact antibiotic dosing and therefore was not clinically significant.

• 出版日期2015-12
• 单位东北大学