Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study

作者：Lew J Q; Chow W H; Hollenbeck A R; Schatzkin A; Park Y^*

来源：British Journal of Cancer, 2011, 104(3): 537-541.

DOI：10.1038/sj.bjc.6606089

• alcohol
• renal cell cancer
• cohort

BACKGROUND: The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear.
METHOD The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n = 49 2187, 1814 cases).
RESULTS: Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <3C and >= 30g per day was, 0.75 (0.63-0.90) and 0.71 (0.59-0.85), respectively, in men and 0.67 (0.42-1.07) and 0.43 (0.22-0.84), respectively, in women.
CONCLUSION: Alcohol consumption was inversely associated with RCC in a dose-response manner. The inverse association may be extended to >= 30 g per day of alcohol intake. British Journal of Cancer (2011) 104, 537-541. doi:10.1038/sj.bjc.6606089 www.bjcancer.

• 出版日期2011-2-1