An unusual case of pedunculated subserosal leiomyosarcoma of the uterus mimicking ovarian carcinoma

作者：Suh Dong Soo; Kim Yoon Hwa; Yun Ka Yeong; Lee Nam Kyung; Choi Kyung Un; Kim Ki Hyung^*; Yoon Man Soo

来源：Journal of Ovarian Research, 2016, 9(1): 2.

DOI：10.1186/s13048-016-0212-4

• Leiomyosarcoma
• Postmenopausal
• Pedunculated

Background: Leiomyosarcoma of the uterus is an extremely rare but highly aggressive tumor that accounts for only 1-2 % of uterine malignancies, and is usually associated with a dismal outcome.
Case presentation: The authors present an unusual case of pedunculated subserosal leiomyosarcoma of the uterus mimicking ovarian carcinoma. A 57-year-old postmenopausal woman presented with progressive low abdominal pain and urinary frequency. Pelvic magnetic resonance imaging revealed a large adnexal mass with carcinomatosis peritonei. Laboratory examination revealed an elevated serum CA-125 level (398.4 U/ml). The patient underwent exploratory laparotomy under suspicion of ovarian malignancy. Frozen section indicated malignancy originating from the uterus, and thus, total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, pelvic and para-aortic lymph node dissection, and mass excision were performed. Subsequent histopathologic examination resulted in a final diagnosis of leiomyosarcoma of the uterus. The patient's postoperative course was uneventful, and gemcitabine and docetaxel adjuvant chemotherapy was administered.
Conclusion: The authors report an unusual case of pedunculated subserosal leiomyosarcoma of the uterus mimicking ovarian carcinoma.

• 出版日期2016-2-9