MANGANESE PERCHLORATE-CATALYZED GREENER SYNTHESIS OF 12-ARYL OR 12-ALKYL-8,9,10,12-TETRAHYDROBENZO[alpha]XANTHEN-11-ONE DERIVATIVES UNDER ULTRASONICATION

作者：Kaur Bhupinder; Parmar Anupama; Kumar Harish^*

来源：Synthetic Communications, 2012, 42(3): 447-453.

DOI：10.1080/00397911.2010.525677

• Manganese perchlorate hydrate
• multicomponent reaction
• ultrasonic irradiation
• xanthenes

A greener and more efficient protocol for the synthesis of 12-aryl or 12-alkyl-8,9,10,12-tetrahydrobenzo[alpha]xanthen-11-one derivatives has been developed via one-pot, three-component reaction of aromatic aldehydes, 2-naphthol, and 1,3-cyclohexadione or 5,5-dimethyl 1,3-cyclohexadione using manganese perchlorate hydrate as a catalyst under ultrasonic irradiation. Good yield, shorter reaction time, simple workup procedure, and milder reaction conditions make this protocol efficient and environmentally benign.

• 出版日期2012