Water-Soluble Red Pigment Production by Paecilomyces sinclairii and Biological Characterization

作者：Choi Jang Won; Park Jong Pil^*

来源：Biotechnology and Bioprocess Engineering, 2018, 23(2): 246-249.

DOI：10.1007/s12257-018-0103-1

• natural pigment
• Paecilomyces sinclairii
• antimicrobial activity
• fractionation
• chemical structure

Natural pigments have several advantages over synthetic colorants. In this study, the production of red pigment produced by Paecilomyces sinclairii in microbial fermentation was demonstrated and the pigment was purified and characterized. The red pigment was produced from submerged fungal fermentation and fractionated by medium pressure flash chromatography. After fractionation, the spectrophotometric characterization of the red pigment revealed an lambda(max) at 520 nm. Antimicrobial activity of the red pigment fraction was also studied against Escherichia coli O157 and Pseudomonas aeruginosa PAO1. The fraction (F2-F6) of the red pigment exhibited broad-spectrum antimicrobial activity in both bacteria. These results demonstrate the potential of this pigment in inhibiting bacterial growth and in food processing and other foodrelated applications.

• 出版日期2018-3