A Novel Tautomeric Polymorph of Anhydrous Guanine and Its Reversible Water Harvesting Property

作者：Chen, Fenghua; Ma, Yurong^*; Wang, Yingxia; Qi, Limin^*

来源：Crystal Growth & Design, 2018, 18(11): 6497-6503.

DOI：10.1021/acs.cgd.8b00606

• PROTON-TRANSFER
• G-QUARTET
• ARCHITECTURES
• DESMOTROPY
• STABILITY
• SCAFFOLDS
• MODEL

Tautomeric isomerism is very important in DNA/RNA research, especially base-pair mismatches. However, the tautomeric polymorph of anhydrous guanine (AG) composed of a N-7-G purine ring has never been reported in the literature. Herein, a novel crystal phase of anhydrous guanine consisting of a N-9-G purine ring was obtained by dehydration of guanine monohydrate (GM) at 111 degrees C, termed dehydrated-GM, the first reported tautomeric polymorph of AG (N-7-G). The dehydration/hydration transformation between GM and dehydrated-GM can be repeated more than 10 times without any observable phase damage. The dehydrated-GM can harvest 8 wt % water within 30 min at relative low humidity (below 20%). Furthermore, dehydrated-GM has long-term stability in a very dry environment when the temperature is in between RT and 150 degrees C. The channel structure of dehydrated-GM can enlighten the design of materials to harvest water from atmospheric air. The tautomeric polymorphism of N-7-G and N-9-G purine rings provides a new insight in nucleic acid bases crystals.

• 出版日期2018-11
• 单位北京理工大学; 北京大学