Analysis of CYP3A inhibitory components of star fruit (Averrhoa carambola L.) using liquid chromatography-mass spectrometry

作者：Hosoi Shinzo^*; Shimizu Eri; Arimori Kazuhiko; Okumura Manabu; Hidaka Muneaki; Yamada Mitsuko; Sakushima Akiyo

来源：Journal of Natural Medicines, 2008, 62(3): 345-348.

DOI：10.1007/s11418-008-0239-y

• CYP3A
• star fruit
• Averrhoa carambola
• enzyme inhibitor
• catechin
• LC-MS

In this study, we analyzed the CYP3A inhibitory components of star fruit Averrhoa carambola L., using liquid chromatography-mass spectrometry (LC-MS). The stereoisomer of procyanidin B1 and B2 and/or the trimer consisting of catechin and/or epicatechin were suggested to be potent inhibitory components.

• 出版日期2008-7