Antimicrobial activities of the whole plant of Cestrum nocturnum against pathogenic microorganisms

作者:Khan Murad Ali*; Inayat Humaira; Khan Haroon; Saeed Mohammmad; Khan Ikhtair; Inayat Ur Rahman
来源:African Journal of Microbiology Research, 2011, 5(6): 612-616.

摘要

The crude methanol extract of the whole plant of Cestrum nocturnum L. (Solanaceae) and its subsequent fractions were tested against various bacterial and fungal strains. With the exception of Salmonella typhi, the tested samples showed marked antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aurous, Bacillus subtilis, Escherichia coli and Shigella flexenari. The minimum inhibitory concentrations (MICs) ranged from 19 to 280 mu g/ml. The crude extract and fractions were also susceptible to Candida species and Microsporium canis. The minimum inhibitory concentrations (MICs) for various fungi ranged from 170 to 290 mu g/ml. In phytochemical analysis, the crude form and fractions of plant showed the presence of various phytochemical chemical groups like glycosides, alkaloids, saponins, phenols, flavonoids, sterols and tannins. Therefore, the current findings can be attributed to these groups.

  • 出版日期2011-3-18