Asymmetric, Organocatalytic Bromolactonization of Allenoic Acids

作者：Wilking Michael; Daniliuc Constantin G; Hennecke Ulrich^*

来源：Synlett, 2014, 25(12): 1701-1704.

DOI：10.1055/s-0034-1378278

• allenes
• asymmetric synthesis
• cyclization
• electrophilic addition
• halogenation

Asymmetric, reagent-controlled bromolactonizations of allenoic acids have been achieved by using (DHQD)(2)PHAL as catalyst. A range of substrates can be cyclized in good yields and moderate to good enantioselectivities under operationally simple conditions.

• 出版日期2014-7