An Unprecedented Method for the Generation of tert-Butylperoxy Radical Using DIB/TBHP Protocol: Solvent Effect and Application on Allylic Oxidation

作者：Zhao Yi; Yeung Ying Yeung^*

来源：Organic Letters, 2010, 12(9): 2128-2131.

DOI：10.1021/ol100603q

tert-Butylperoxy radical was generated with PhI(OAc)(2) and tBuOOH. Ester solvent was found to be critical and the protocol was applied in the allylic oxidation of various olefinic substrates, which gave the corresponding alpha,beta-unsaturated enones in good yield and regioselectivity.

• 出版日期2010-5-7