Digital biomagnetism: Electrodeposited multilayer magnetic barcodes

作者:Palfreyman Justin J*; Cooper Joshaniel F K; van Belle Friedo; Hong Bingyan; Hayward Tom J; Lopalco Maria; Bradley Mark; Mitrealias Thanos; Bland J Anthony C
来源:Journal of Magnetism and Magnetic Materials, 2009, 321(10): 1662-1666.
DOI:10.1016/j.jmmm.2009.02.109

摘要

A novel magnetic encoding technique for performing high-throughput biological assays is presented. Electrodeposited Ni/Cu and Co/Cu multilayer pillar structures with a diameter of 15 mu m and a thickness up to 10 mu m are presented as "magnetic barcodes", where the number of unique codes possible increases exponentially with a linear increase in length. A gold cap facilitates the growth of self-assembled monolayers (SAMs), while microdrop printing allows efficient generation of large libraries of tagged probes. Coercivity-tuning techniques are used to exploit a non-proximity encoding methodology compatible with microfluidic flow.

  • 出版日期2009-5