A Cytokine-Dependent Switch for Glial-Neuron Interactions

作者:Lee So Young; Haydon Philip G*
来源:Neuron, 2011, 69(5): 835-837.
DOI:10.1016/j.neuron.2011.02.033

摘要

Though transmitters can be released from astrocytes, the conditions that permit their modulation of synaptic transmission are under debate. Santello et al. in this issue of Neuron now show that TNF alpha promotes a burst mode of glial transmitter release that escapes reuptake processes allowing access to neuronal NMDA receptors.

  • 出版日期2011-3-10