摘要
Defects in the function of cellular organelles such as peroxisomes, lysosomes and mitochondria are well-known causes of human diseases. Recently, another organelle has also been added to this list. Cilia-tiny hair-like organelles attached to the cell surface-are located on almost all polarized cell types of the human body and have been adapted as versatile tools forvarious cellular functions, explaining why cilia-related disorders can affect many organ systems. Several molecular mechanisms involved in cilia-related disorders have been identified that affect the structure and function of distinct cilia types.
- 出版日期2007-11