A folic acid conjugated silica-titania porous hollow nanosphere for improved topical photodynamic therapy

作者:Jang Yoonsun; Kim Sojin; Oh Wan Kyu; Kim Chanhoi; Lee Inkyu; Jang Jyongsik*
来源:Chemical Communications, 2014, 50(97): 15345-15347.
DOI:10.1039/c4cc07457b

摘要

The folic acid conjugated hollow nanosphere is used to encapsulate protoporphyrin IX and is utilized for photodynamic therapy. This system represents a 3.33 times higher photodynamic efficiency than previous protoporphyrin IX-based systems. The result proposes a new opportunity for effective photodynamic therapy of folate receptor positive tumor cells.

  • 出版日期2014