An efficient synthesis of 3-ethoxypyrrolidine-2,5-diones and cis-2,3,3a,6a-tetrahydrofuro[2,3-c]pyrrole-4,6(5H)-diones from beta-cyanocarboxylic acids

作者：Zanatta Nilo^*; da Silva Fabio M; da Silva Andreia M P W; Aquino Estefania da C; Bonacorso Helio G; Martins Marcos A P

来源：ARKIVOC, 2012, 1-12.

• beta-Cyanocarboxylic acids
• succinimides
• pyrrolidin-2,5-diones
• primary amines

A simple and convenient procedure for the synthesis of a new series of 3-ethoxypyrrolidine-2,5-diones and cis-2,3,3a,6a-tetrahydrofuro[2,3-c]pyrrole-4,6(5H)-diones derivatives is described. All compounds were obtained from the direct cyclization of two beta-cyanocarboxylic acids with primary amines and amino alcohols in short reaction time and good yields.

• 出版日期2012