促性腺激素释放激素激动剂及拮抗剂在体外受精-胚胎移植应用的比较

作者：曹云霞; 胡频

来源：生殖医学杂志, 2007, (05): 323-324.

DOI：10.3969/j.issn.1004-3845.2007.05.015

• 促性腺激素释放激素激动剂
• 促性腺激素释放激素拮抗剂
• 体外受精-胚胎移植
• 控制性卵巢刺激

GnRH agonist(GnRH-a) and GnRH antagonist(GnRH-ant) play important roles in in-vitro fertilization and embryo transfer(IVF-ET).The effect of GnRH-a was affirmed during twenty years'use.The application of GnRH-ant was comparatively less because some advantages of GnRH-a has not been recognized and now researchers pay much attention on it.So,its useness become more and more in the cycles of controlled ovarian stimulation(COS).Up to now,identical conclusion on which kind of the GnRH analogue is more superior for the results of IVF-ET has not been got.As for GnRH-ant,much investigation should be done and a lot of biological rationale and convincing clinic data should be acquired so as to proving which will be better.

• 出版日期2007
• 单位安徽医科大学第一附属医院