A new strategy for diurnal intraocular pressure curve

作者：Borrone Roberto^*

来源：European Journal of Ophthalmology, 2012, 22(6): 964-971.

DOI：10.5301/ejo.5000182

• Diurnal intraocular pressure curve
• Glaucoma
• Intraocular pressure
• Intraocular pressure fluctuation

PURPOSE. To investigate whether there is agreement between intraocular pressure (IOP) readings in the supine position at 6 AM upon awaking (before getting out of bed) and the IOP at 8 Ann, also measured in supine position after remaining 30 minutes in this position. %26lt;br%26gt;METHODS. In a sample of 50 eyes of 50 patients (normal, glaucoma suspect, and glaucoma patients), 6 AM IOP was measured in the supine position upon awaking and before getting up, while 8 AM IOP was measured on the same day, also in the supine position after 30 minutes in this position. %26lt;br%26gt;RESULTS. The IOP values at 6 Am were mean 16.06+/-3 mmHg; median 15.5 mmHg (range 10-25.5 mmHg). For the 8 AM readings, the average was 15.94+/-4 mmHg and the median 15 mmHg (range 10-25.5 mmHg). The difference between mean 6 and 8 AM IOPs was 0.13+/-0.9 mmHg (confidence interval -0.14 to 0.40). Pearson correlation coefficient between the 6 and 8 AM IOPs for the total sample was r=0.97 (p%26lt;0.05). There were no significant differences in behavior regarding eyes with high IOP as compared to normal IOP eyes (repeated-measure analysis of variance, p=0.72). %26lt;br%26gt;CONCLUSIONS. The 8 AM IOP readings obtained in the supine position and under the conditions described were equivalent to 6 AM IOP readings (as the first measure of the diurnal pressure curve [DPC]). This new strategy for DPC will make it a widely used tool in daily practice since it spares the need for hospitalization or home measurements.

• 出版日期2012-12