A Novel Herbomineral Formulation Sahaj Vati as Shelf Life Enhancer of Nutraceuticals Based on Aflatoxin Inhibitory and Antioxidant Activity

作者：Yadav K D; Dwivedy A K; Chaudhary A K; Dubey N K^*

来源：Indian Journal of Pharmaceutical Sciences, 2017, 79(1): 29-34.

DOI：10.4172/pharmaceutical-sciences.1000197

• Herbomineral formulation
• shahaj vati
• antiaflatoxigenic
• antioxidant
• nutraceuticals

Yadav, et al.: Sahaj Vati a Herbomineral Product as Antiaflatoxin and Antioxidant
The present investigation deals with chemical standardization and aflatoxin inhibitory and antioxidant activity of a herbomineral formulation, sahaj vati prepared in two batches (batch I and II) by mixing shilajeet (thick exudates of the mountain during summer season), guggul (Commiphora mukul (stocks) hook.), haridra (Curcuma longa L) and chitrak (Plumbago zeylanica L) with levigation of Agnimantha kwatha (Premna mucronata L). Batch I was prepared by mixing shilajeet, guggul, haridra and chitrak in equal proportion (25% each by weight) while batch II comprised shilajeet (44.7%), guggul (44.7%), haridra (4.8%) and chitrak (5.8%) by weight. Sahaj vati II showed highest (96%) inhibition of aflatoxin production at concentration of 10 000 mu g/ml. Suddha guggul exhibited strong antioxidant activity showing lowest IC50 at concentration of 20.56 mu g/ml. Based on these findings, the newly formulated herbomineral formulation could be recommended for value addition of nutraceuticals by enhancing their shelf life against lipid per oxidation and aflatoxin contamination.

• 出版日期2017-2
• 单位河北医科大学