PLEKHA5: A Key to Unlock the Blood-Brain Barrier?

作者:Eisele Sylvia C; Gill Corey M; Shankar Ganesh M; Brastianos Priscilla K*
来源:Clinical Cancer Research, 2015, 21(9): 1978-1980.
DOI:10.1158/1078-0432.CCR-14-2604

摘要

Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the brain is limited. PLEKHA5 functions as a regulator of brain metastasis in melanoma, and further investigation is warranted to explore the use of PLEKHA5 as a potential therapeutic target.

  • 出版日期2015-5-1