Left ventricular long-axis function: Reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of z-score values

作者：Koestenberger Martin^*; Nagel Bert; Ravekes William; Avian Alexander; Heinzl Bernd; Fritsch Peter; Fandl Andrea; Rehak Thomas; Gamillscheg Andreas

来源：American Heart Journal, 2012, 164(1): 125-131.

DOI：10.1016/j.ahj.2012.05.004

Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. %26lt;br%26gt;Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m(2)). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. %26lt;br%26gt;Results The MAPSE ranged from a mean of 0.57 cm (z-score +/- 2: 0.38-0.76 cm) in neonates to 1.63 cm (z-score +/- 2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age (r = 0.87, P %26lt; .001) and BSA (r = 0.89, P %26lt; .001) with a nonlinear course. There was no significant difference in MAPSE values between females or males. A positive correlation was found between MAPSE values and LV ejection fraction values (r = 0.28, P %26lt; .001). %26lt;br%26gt;Conclusions Z-scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future. (Am Heart J 2012;164:125-31.)

• 出版日期2012-7
• 单位河北医科大学