Uniform modeling of bacterial colony patterns with varying nutrient and substrate

作者：Schwarcz Deborah; Levine Herbert; Ben Jacob Eshel; Ariel Gil^*

来源：Physica D: Nonlinear Phenomena , 2016, 318: 91-99.

DOI：10.1016/j.physd.2015.11.002

• Pattern formation
• Bacterial colonies
• Reaction-diffusion model
• Random lattice

Bacteria develop complex patterns depending on growth condition. For example, Bacillus subtilis exhibit five different patterns depending on substrate hardness and nutrient concentration. We present a unified integro-differential model that reproduces the entire experimentally observed morphology diagram at varying nutrient concentrations and substrate hardness. The model allows a comprehensive and quantitative comparison between experimental and numerical variables and parameters, such as colony growth rate, nutrient concentration and diffusion constants. As a result, the role of the different physical mechanisms underlying and regulating the growth of the colony can be evaluated.

• 出版日期2016-4-1