Disease or adaptation: another look at the practice of medicine

作者：Soeters Peter B; De Leeuw Peter W^*

来源：Postgraduate Medicine, 2018, 130(2): 239-243.

DOI：10.1080/00325481.2018.1433435

• Pathophysiology
• homeostasis
• insulin resistance
• wound healing
• adaptation

The practice of medicine has changed considerably over the past few decades and is now focusing more and more on early intervention strategies. As a result, we tend to consider pre-symptomatic abnormalities, however small, already as a potential target for treatment. In this viewpoint, we argue that we should put more emphasis on pathophysiological thinking as many of the so-called early abnormalities may, in fact, reflect adaptive mechanisms rather than disease. This view should influence medical care and education, emphasizing the importance of knowledge of pathophysiology.

• 出版日期2018