A new and efficient method for the synthesis of alpha,alpha-dihaloketones by oxyhalogenation of alkynes using oxone (R)-KX (X = Cl, Br, or I)

作者：Madabhushi Sridhar^*; Jillella Raveendra; Mallu Kishore Kumar Reddy; Godala Kondal Reddy; Vangipuram Venkata Sairam

来源：Tetrahedron Letters, 2013, 54(30): 3993-3996.

DOI：10.1016/j.tetlet.2013.05.072

• Oxone (R)
• Potassium halide
• Oxyhalogenation
• Alkynes
• alpha,alpha-Dihaloketones

A simple and efficient method for the preparation of alpha,alpha-dichloroketones, alpha,alpha-dibromoketones, and alpha,alpha-diiodoketones by oxyhalogenation of alkynes using oxone and MX (X = Cl, Br, or I) is described.

• 出版日期2013-7-24