An air-stable half-sandwich Ru-II complex as an efficient catalyst for [3+2] annulation of 2-arylcyclo-2-enones with alkynes

作者：Zhao, Yinsong; He, Zhen; Li, Shiqing; Tang, Junbin; Gao, Ge^*; Lan, Jingbo; You, Jingsong^*

来源：Chemical Communications, 2016, 52(25): 4613-4616.

DOI：10.1039/c5cc10169g

• H BOND ACTIVATION
• DIRECT ORTHO ARYLATION
• C-C
• AROMATIC KETIMINES
• INTERNAL ALKYNES
• ORGANIC HALIDES
• RUTHENIUM
• ALKENES
• FUNCTIONALIZATION
• ALKENYLATION

An air-stable half-sandwich rutheniumII complex, [Ru(p-cymene)(MeCN)(3)](SbF6)(2), was synthesized and characterized. It exhibited unique catalytic ability in a [3+ 2] annulation reaction of 2-arylcyclo-2-enones with internal alkynes via C(sp(2))-H/alkene functionalization, which offered a rapid and atom-economical methodology to construct various synthetically challenging spiro carbocyclic indenes bearing a quaternary carbon.

• 出版日期2016
• 单位四川大学